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Channel Posts
Correct Answer - A
Ans: A. Lead poisoning
Findings
Microcytic Anemia - Iron Deficiency
Hypersegmented Neutrophils - B12 and Folic Acid Deficiency
Young & No H/o Of Alcohol Consumption [Patient came with a
history of Fatigue and Tiredness] - Chronic Alcoholism can be ruled
out
Hemolytic Anemia - may demonstrate red blood cell fragments
called schistocytes, red blood cells that look like spheres
(spherocytes), and/or red blood cells missing small pieces (bite
cells). An increased number of newly made red blood cells
(reticulocytes) may also be a sign of bone marrow compensation for
anemia.
1 99320
| 2 | Voting A 23-year-old male presented with
history f fatigue& tiredness On
investigation, he found t hv Hb values of 9gm%, MCV of 101 FL. peripheral smear examination showed microcytic RBC and hypersegmented neutrophils. Which is most probable etiology | 7 400 |
| 3 | Correct Answer - D
Ans: D. Unidirectional locomotion of neutrophils
Chemotaxis is defined as a unidirectional movement of leukocytes
up to a concentration gradient of chemotactic molecules. All
granulocytes, monocytes and to a lesser extent lymphocytes
respond to chemotactic stimuli with varying rates of speed.
Chemoattractants are exogenous or endogenous. Exogenous
agents are bacterial products. Endogenous mediators are:
Components of complement pathway C5a
Products of lipoxygenase pathway LTB4
Cytokines particularly those of chemokine families. | 4 599 |
| 4 | Voting What is the main feature of chemotaxis
as observed in white blood cells? | 10 981 |
| 5 | Correct Answer - A
Answer- A- Immunochromatography assays
HBV chronic carriers are those in whom HBsAg persists for more
than 6 months in the presence of HBeAg or anti-HBe. HBsAg may
persist for years after the loss of HBeAg. The most useful detection
methods are enzyme-linked Immunosorbent assay for HBV
antigens and antibodies and PCR for viral DNA -Jawetz 27/e pg-
504
Serological assays detect the host immune response (antibodies to
HCV) or a viral antigen (HBsAg, HCVcAg). They are based on the
immunoassay principle and are available in the form of rapid
diagnostic tests (RDTs) or laboratory-based enzyme immunoassays
(EIAs), chemiluminescence immunoassays (CLIAs) and
electrochemiluminescence immunoassays (ECLs). | 6 730 |
| 6 | Voting HbsAg is based on which principle | 14 227 |
